Target protein

Results: 215



#Item
61Molecular biology / Protein biosynthesis / 4EGI-1 / Molecules / EIF4E / EIF4G / Mammalian target of rapamycin / Eukaryotic initiation factor / Bleb / Biology / Programmed cell death / Gene expression

An eIF4E-interacting peptide induces cell death in cancer cell lines

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Source URL: www.nature.com

Language: English - Date: 2014-10-30 09:37:15
62Proteins / Hsp27 / Heat shock protein / Ribbon symbolism / Gemcitabine / Pancreatic cancer / Prostate cancer / Proteasome / Mammalian target of rapamycin / Biology / Medicine / Oncology

OGX-427 inhibits tumor progression and enhances gemcitabine chemotherapy in pancreatic cancer

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Source URL: www.nature.com

Language: English - Date: 2011-10-20 05:59:58
63Cullin / Autophagy / NEDD8 / CAND1 / BTRC / Tuberous sclerosis protein / Von Hippel–Lindau tumor suppressor / CUL1 / Ubiquitin / Biology / Proteins / Mammalian target of rapamycin

Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis

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Source URL: www.nature.com

Language: English - Date: 2012-09-06 06:12:07
64Protein kinases / Cell cycle / Tumor suppressor genes / Proteins / CDKN1B / Hypoxia-inducible factors / P27 / C-Raf / Mammalian target of rapamycin / Biology / Cell biology / Signal transduction

OPEN Citation: Cell Death and Disease[removed], e1535; doi:[removed]cddis[removed] & 2014 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis

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Source URL: www.nature.com

Language: English - Date: 2014-11-20 08:37:21
65Programmed cell death / Glial cells / Neurobiology / Anoikis / Astrocyte / Phosphoinositide 3-kinase / Glial fibrillary acidic protein / Mammalian target of rapamycin / AKT / Biology / Cell biology / Apoptosis

βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis

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Source URL: www.nature.com

Language: English - Date: 2011-10-13 06:00:02
66Apoptosis / Programmed cell death / Proteins / Oncology / Survivin / Telomerase / Carcinogenesis / P53 / Bcl-2-associated X protein / Biology / Medicine / Cell biology

WRAP53 promotes cancer cell survival and is a potential target for cancer therapy

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Source URL: www.nature.com

Language: English - Date: 2011-01-13 05:57:04
67Cell signaling / Signal transduction / Programmed cell death / Oncology / AKT / Phosphoinositide 3-kinase / Mammalian target of rapamycin / Autophagy / Apoptosis / Biology / Cell biology / Protein kinases

OPEN Citation: Cell Death and Disease[removed], e804; doi:[removed]cddis[removed] & 2013 Macmillan Publishers Limited All rights reserved[removed]www.nature.com/cddis

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Source URL: www.nature.com

Language: English - Date: 2013-09-19 09:55:33
68Microbiology / Cellular processes / Molecular biology / Autophagy / Sirolimus / Atg1 / Bcl-2-associated X protein / Trypan blue / Mammalian target of rapamycin / Biology / Programmed cell death / Apoptosis

[removed]Protects against stress-induced apoptosis

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Source URL: www.nature.com

Language: English - Date: 2012-07-12 05:54:00
69Macrolides / Biology / Biguanides / Guanidines / Chemistry / Metformin / Mammalian target of rapamycin / Sirolimus / AMP-activated protein kinase / Medicine / Protein kinases / Lymphoma

Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

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Source URL: www.nature.com

Language: English - Date: 2012-03-01 05:57:38
70Crystallography / Protein structure / Cell biology / Green fluorescent protein / Autophagy / Crystal / Protein crystallization / Cell / Protein / Biology / Protein methods / Bioluminescence

Cells target giant protein crystals for degradation

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Source URL: phys.org

Language: English - Date: 2015-04-16 10:17:14
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